Manchester City lead the way, but Liverpool and Arsenal can pile the pressure on the champions before City next play a league game.
Mikel Arteta and Jurgen Klopp will be looking to heap pressure on Pep Guardiola Due to City's participation in their FA Cup semi-final against Chelsea, live on talkSPORT, the Reds and Gunners play two Premier League games before Pep Guardiola's men.
Arsenal start with a Saturday evening trip to Wolves before welcoming Chelsea to the Emirates, with both games exclusively live on talkSPORT.
Meanwhile, Liverpool travel to Fulham on Sunday and then head to Everton for a crucial Merseyside derby next Wednesday.
This is how things stand heading into the double gameweek 3
Arsenal have the chance to redeem themselves in the league with back-to-back gamesCredit: AFP At the other end of the table, Everton play twice.
Then, of course, they welcome Jurgen Klopp for his final Merseyside derby.
Sheffield United are also playing two games, welcoming Burnley on Saturday before facing a trip to Old Trafford to play Manchester United the following Wednesday.
Elsewhere, Wolves have a double gameweek, starting with that match against Arsenal before welcoming Bournemouth on Tuesday.
Why has Everton vs Nottingham Forest been given an early kick-off time this weekend?
And finally, Crystal Palace face West Ham before hosting Newcastle at Selhurst Park.
Below, you can see the full Gameweek 34 fixture list including kick-off times and talkSPORT commentary details.
Mark Goldbridge snubs Manchester City as he names Chelsea, Tottenham & Arsenal stars in his Premier League Team Of The Season Premier League fixtures April 20 - April 25
Saturday, April 20
Luton vs Brentford - 3pm
Sheffield United vs Burnley - 3pm - talkSPORT 2 exclusive
Wolves vs Arsenal - 7:30pm - talkSPORT exclusive
Sunday, April 21
Everton vs Nottingham Forest - 1:30pm
Aston Villa vs Bournemouth - 3pm
Crystal Palace vs West Ham - 3pm
Fulham vs Liverpool - 4:30pm
Tuesday, April 23
Arsenal vs Chelsea - 8pm - talkSPORT exclusive
Wednesday, April 24
Wolves vs Bournemouth - 7:45pm - talkSPORT App exclusive
Crystal Palace vs Newcastle - 8pm - talkSPORT App exclusive
Everton vs Liverpool - 8pm - talkSPORT exclusive
Manchester United vs Sheffield United - 8pm - talkSPORT 2 exclusive
Thursday, April 25
Brighton vs Manchester City - 8pm - talkSPORT exclusive
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